Overview of Estrace Medicine:
Progynova is used for the treatment of hormone-mediated disease like osteoporosis and to treat breast cancers also. It is also used to treat the symptoms of menopause called hot flashes, vaginal drying, and itching etc. The main constituent of Progynova tablet is estradiol which is the form of female sex hormone estrogen produced by the ovaries.
Mechanism action of Estrace Tablet:
The active component of Progynova is estradiol valerate which is a naturally occurring form of female sex hormone oestrogen.
Estradiol is an estrogen or agonist of nuclear estrogen receptors. It is an agonist of membrane estrogen receptors.
Dosage and how to use Estrace Medicine:
Progynova is available in 1 mg and 2 mg tablets. The strength of the medicine is decided by the doctor. Usually one tablet is taken once daily. The tablets should be taken at the same time each day. It can be taken with or without food. Progynova comes in convenient blister packs marked with the days of the week.
Contraindications of Estrace:
Estrace-Progynova-Estradiol is contraindicated in the below mentioned conditions-
Estrace-Progynova-Estradiol interacts with various medicines like amiodarone, antifungal agent like Itraconazole, Ketoconazole, aprepitant, carbamazepine, cimetidine, clarithromycin, fluoxetine, fluvoxamine and griseofulvin.
Side effects of Estrace Medicine:
The side effects associated with the use of estrace-progynova estradiol are- headache, nausea, vomiting, and constipation, pain in breast, constipation, gas, heartburn, weight gain, hair loss, skin irritation, swelling and redness of vagina, painful menstrual periods, anxiety, depression, muscle pain, runny nose and cough.
Missed dose of Estrace:
If a dose is missed and 12 hours have not passed, the missed dose should be taken as soon as possible and the next dose is taken at the usual time. If a dose has been forgotten and more than 12 hours are gone, missed dose is skipped and next dose is taken as usual. Never take double dose to make up the missed dose.
If the medicine is taken in excess, it can lead to adverse effects like nausea, vomiting and vaginal bleeding. Seek medical help in such a case.
Safety measures of Estrace:
Storage of Estrace:
Estrace estradiol should be stored properly at room temperature away from direct heat, light and moisture. It should be kept away from children and pets.