Overview of Ganfort Eye Drop:
Ganfort eye drops are used to treat ocular hypertension i.e. raised pressure in the eye. It is also used to treat open angle glaucoma. These eye drops are available in multi-dose bottles or preservative-free single-dose containers.
Mechanism of action of Ganfort Eye Drop:
The main active ingredients in Ganfort eye drops are Bimatoprost and timolol maleate. These medicines are responsible to decrease the raised pressure within the eyes. These medicines work in different ways to produce a combined effect.
Normally, pressure within the eyeball is naturally maintained by the continuousflow of liquid called aqueous humour through the eyeball. Aqueous humour is formed by the ciliary body in the eyes. It drains out of the eyeball through channels which are called trabecular meshwork. If the outflow of aqueous humour is blocked, the aqueous humour builds up inside the eye and increases the pressure within the eyeball. This raised pressure can damage the optic nerve and can impair the vision, so it needs to be reduced.
Bimatoprost reduces the pressure in the eye by copying the action of a naturally-occurring prostaglandin. Prostaglandins are a group of natural body chemicals which are found in various places in the body. In the eye, they increase the drainage of the aqueous humour out of the eyeball. Bimatoprost works by enhancing the drainage of aqueous humour out of the eyeball. This decreases the pressure within the eye.
Timolol is a type of beta blocker. Blocking of beta receptors in the eye results in the reduction of produced aqueous humour. Timolol therefore reduces the inflow of aqueous humour into the eyeball and hence decreases the pressure within the eye in a different way.
Dosage and how to use Ganfort Eye Drop:
The hands should be washed properly before using these eye drops. One drop should be put in the affected eye once in a day and at the same time every day. It can be in the morning or in the evening. The medicine shows effective results if it is applied in the evening.
After administering the eye drops, the eye should be closed and tear duct is pressed (at the corner of the eye closest to your nose) for about two minutes to minimise the amount of medicine that is absorbed into the bloodstream.
Contraindications of Ganfort:
Ganfort eye drops are contraindicated in various situations like-
Drug interactions of Ganfort Eye Drop:
Along with Ganfort eye drops, following mentioned drugs should not be taken:
Beta blockers e.g. atenolol, calcium channel blockers e.g. nifedipine, verapamil, diltiazem and digoxin, medicines for abnormal heart rhythms e.g. amiodarone.
The combination of these medicines along with Ganfort eye drops results in low blood pressure or low heart rate in the patient.
Side effects of Ganfort Eye Drop:
Medicines and their likely side effects can affect individual people in different ways. The following are some of the side effects which are associated with this medicine.
Very common side effects includes-
Redness in the eyes due to increased blood supply, growth of eyelashes. The common side effects includes irritation in eye including stinging, burning, itching in the eyes, sensation of something in the eyes, dry eyes, pain in eye, redness, itching or swelling of eyelid, photophobia, corneal erosion, eye discharge, darkening of eyelid. Uncommon side effects includes headache, inflammation of eyelid, inflammation of iris, change in the colour of the iris, watery eyes, strain in the eye and inflammation of the lining of nose. Some other side effects includes double vision, pain in chest, dizziness, low blood pressure, breath shortening, depression and difficulty in sleeping.
If a dose is missed, next dose should be applied as usual. Never use the drops twice in a day to make up the missed dose.
Safety measures of Ganfort Eye Drop: