Overview of Abortion-pill:
Abortion pills are used to terminate pregnancy of approximately 7 weeks. The popular abortion pills are named as mifepristone and misoprostol. These pills are also helpful in the treatment of brain tumor, endometriosis and fibroids. The abortion pill is approved by the FDA to terminate the pregnancy during the first 10 weeks of development. Abortion pills are easy and safe to use at home.
Mechanism of action of Abortion-pill:
The abortion pills are antiprogestational steroids. These pills ceases the activity of progesterone, which is a vital hormone in providing nutrition to the fetus and in the continuation of pregnancy.
The process of abortion starts as the first pill is taken. Initially a pill of mifepristone is taken. To survive pregnancy, progesterone hormone is necessary. Mifepristone blocks progesterone. Sometimes bleeding start to occur after taking mifepristone but it is not common. So, misoprostol is taken after 24 to 48 hours of taking the first pill. The medicine causes cramping and bleeding after 3 to 4 hours of taking misoprostol to empty the uterus. Large blood clots may appear. Generally, the pregnancy tissue gets cleared within 4 to 5 hours.
The last step of abortion is follow up visit. Ultrasound is done to make sure that the abortion is complete.
Dosage and how to take Abortion-pill:
Abortion pills are to be taken by mouth. When the treatment is started, a single pill should be taken on the first day. After a day, four other pills are to be taken via buccal route. After two hours of taking the medicine, vaginal bleeding starts to begin. Patient should follow ultrasound check up after 7 days to confirm the termination of pregnancy.
Contraindications of Abortion-pill:
Drug interactions of Abortion-pill:
Abortion pills interacts with antifungal drugs(itraconazole, ketoconazole), anticoagulants (warfarin) , corticosteroids (hydrocortisone)and anticonvulsant drugs (carbamazepine, phenobarbital, phenytoin, dexamethasone, rifampin.
Side effects of Abortion-pill:
Some side effects that are seen commonly with the use of abortion pills are – vaginal burning, headache, pain in pelvic region, cramps in stomach, vaginal bleeding, menstrual cycle trouble, excessive bleeding and longer menstrual cycle can also be seen.
Missed dose of Abortion-pill:
Less chances to miss the dose of the medication, because it is usually taken in supervision of the doctor.
If the abortion pills are taken in excess, visit to the doctor immediately.
Storage of Abortion-pill:
These medications should be stored properly at room temperature and completely away from the reach of children and pets. The medicines should be kept away from direct heat, light and moisture.The medicines should not be used after expiry. The expire product should be discarded.